C0283
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C0283
Sigma
L -Carnitine hydrochloride
synthetic, ≥98%
| Synonym: | (−)-β-Hydroxy-γ-(trimethylammonio)butyrate, Vitamin BT |
| CAS Number: | 6645-46-1 |
| Linear Formula: | (CH3)3N+CH2CH(OH)CH2CO2H · Cl- |
| Molecular Weight: | 197.66 |
| EC Number: | 229-663-6 |
| MDL number: | MFCD00066100 |
| PubChem Substance ID: | 24892246 |
Description
| Biochem/physiol Actions | Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production. |
| Packaging | 10 mg in autosmp vl |
Properties
| biological source | synthetic |
| assay | ≥98% |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 2 |
| RTECS | BP2979100 |
References
| reference | Stephens, F.B., et al., New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. J. Physiol. 581, 431-444, (2007) |
| Calvani, M., et al., Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic Res. Cardiol. 95, 75-83, (2000) | |
| Longo, N., et al., Disorders of carnitine transport and the carnitine cycle. Am. J. Med. Genet. 142C, 77-85, (2006) |
